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Updated: Jun 3, 2025

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
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Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

Published on: January 26, 2016

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比斯-3-皮皮里丁:一种用于杀虫剂药物设计的新型动机

Michael Kirchner1, Michael Marner2, Tim Kramer1

  • 1Institute of Organic Chemistry, Justus Liebig University 35392 Giessen Germany Richard.goettlich@org.chemie.uni-giessen.de https://www.uni-giessen.de/de/fbz/fb08/Inst/organische-chemie/AGGoettlich.

RSC advances
|January 13, 2025
PubMed
概括

比斯-3-皮皮里丁作为对寄生虫虫的新抗虫药物具有前景. 几种衍生物有效地降低了寄生虫的活力和机动性,具有最小的细胞毒性,为药物开发提供了潜力.

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Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
Reversible inhibitors display short to medium durations of action. Short-acting agents include simple alcohols with...
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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
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Basicity of Heterocyclic Aromatic Amines01:25

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