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Updated: Jun 3, 2025

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四色单分子成像系统用于跟踪用光HiBiT的GPCR动态

Toshiki Yoda1, Yasushi Sako2, Asuka Inoue1,3

  • 1Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi 980-8578, Japan.

Biophysics and physicobiology
|January 13, 2025
PubMed
概括

研究人员开发了一种新的多色单分子成像方法,使用光标记的HiBiT (F-FiBiTs) 来跟踪活细胞中的G蛋白结合受体 (GPCR). 这种技术可以同时监测多种蛋白质,进步研究细胞信号通路.

关键词:
与G蛋白结合受体的受体是G蛋白结合受体.光标签是一个光标签.信号传导的信号传导.单分子生物物理学的生物物理学.分裂的 luciferase 是一个分裂的 luciferase.

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