静脉血压时间在目标范围内以及心血管疾病和过早死亡
Xu Han1, Shuting Liu1, Xin Zhou1
1Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, China.
JACC. Asia
|January 13, 2025
概括
系统血压 (SBP) 的更高的目标时间范围 (TTR) 与高血压的就业成年人心血管疾病 (CVD) 风险降低和过早死亡有关. 这项研究强调了保持血压在目标范围内的重要性.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 高血压管理 高血压管理
背景情况:
- 之前的研究表明,缩血压目标时间范围 (SBP-TTR) 和不良心血管事件之间存在联系.
- 关于SBP-TTR和心血管结果的现实数据仍然有限.
研究的目的:
- 为了估计SBP-TTR与心血管疾病 (CVD) 和高血压的就业人员的过早死亡之间的关联.
- 提供关于SBP控制对心血管结果的影响的真实数据.
主要方法:
- 包括来自工作场所高血压管理计划的9552名就业参与者.
- 使用线性插值计算SBP-TTR,目标SBP范围为120-140 mmHg.
- 使用多变量考克斯回归来评估心血管疾病,早产心血管疾病和早逝的危险比率 (HR).
主要成果:
- 较高的SBP-TTR与较少的心血管风险因素有关.
- 在SBP-TTR的1-SD增长与心血管疾病风险降低相关 (HR:0.81),过早的心血管疾病风险 (HR:0.76),和过早死亡 (HR:0.83).
- SBP-TTR与缺血性中风 (HR:0.81) 和出血性中风 (HR:0.72) 的风险降低有关,但与心肌梗塞无关.
结论:
- 在就业人员中,SBP-TTR与心血管疾病,早产心血管疾病和早逝风险的降低显著相关.
- 保持SBP在目标范围内对于降低高血压工人心血管风险至关重要.
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