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Updated: Jun 2, 2025

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Published on: February 10, 2023

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在线粒体疾病中重写核表观遗传脚本,作为控制异质体的战略

María J Pérez, Rocío B Colombo, Sebastián M Real

    bioRxiv : the preprint server for biology
    |January 13, 2025
    PubMed
    概括

    向核DNA甲基化有选择地消除具有高水平线粒体DNA (mtDNA) 突变的细胞. 这种表观遗传方法减少了异质体,为线粒体疾病提供了潜在的新疗法.

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