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Updated: Jun 2, 2025

Modeling an Enzyme Active Site using Molecular Visualization Freeware
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Published on: December 25, 2021

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冠状病毒主要蛋白酶的酶动力学模型,包括二元化和连接体结合

Van Ngoc Thuy La1, Lulu Kang2, David D L Minh3

  • 1Department of Biology, Illinois Institute of Technology, Chicago, IL 60616, USA.

bioRxiv : the preprint server for biology
|January 13, 2025
PubMed
概括

这项研究模拟了冠状病毒主要蛋白酶 (MPro),以解释双相度响应曲线. 研究结果揭示了抑制剂和基质如何差异影响MPro二分化和活性,这对于抗病毒药物开发至关重要.

关键词:
贝叶斯回归是一种贝叶斯回归.度 - 反应曲线 (CRC)模度化 (Dimerization) 是一个过程.主蛋白酶 (MPro) 是一个主要的蛋白质酶.中东呼吸系统综合征 (MERS)严重急性呼吸系统综合征 (SARS)

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