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Updated: Jun 2, 2025

In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter
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FGF12A 通过 CaM 监管和 CaM 独立的机制调节 Nav1.5

Lucy Woodbury, Paweorn Angsutararux, Martina Marras

    bioRxiv : the preprint server for biology
    |January 13, 2025
    PubMed
    概括

    细胞内纤维细胞生长因子12A (FGF12A) 通过两个不同的机制调节心脏通道 (Nav1.5) 功能. FGF12A通过calmodulin (CaM) 调节电压依赖的无活化,并独立于CaM抑制持久晚期电流.

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