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Updated: Jun 2, 2025

Microfluidic Mixers for Studying Protein Folding
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阿尔法Fold2的训练集支持其对折叠交换形状的预测

Joseph W Schafer1, Lauren L Porter1,2

  • 1National Library of Medicine, National Center for Biotechnology Information, National Institutes of Health, Bethesda, MD, 20894, USA.

bioRxiv : the preprint server for biology
|January 13, 2025
PubMed
概括

AlphaFold2 (AF2) 可以预测蛋白质结构,但其预测替代形状的能力在很大程度上依赖于训练数据. 进一步开发可能会提高其对折叠切换蛋白的生成能力.

关键词:
折叠切换蛋白质是一种折叠切换蛋白质.变形蛋白质是一种变形蛋白质.蛋白质结构预测 蛋白质结构预测结构生物信息学

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