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Updated: Jun 2, 2025

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
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Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome

Published on: October 3, 2018

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一种突变的ASXL1-EHMT复合体有助于在克隆性血液形成和慢性单核细胞白血病中导致异性染色素功能障碍

Zhen Dong, Hugo Sepulveda, Leo J Arteaga-Vazquez

    bioRxiv : the preprint server for biology
    |January 13, 2025
    PubMed
    概括

    ASXL1的突变破坏了异色染色体的完整性,导致可转移元素的表达增加,并可能导致与年龄相关的克隆性血液形成和髓状瘤.

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    Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up09:01

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