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Updated: Jun 2, 2025

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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Published on: February 1, 2019

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通过微米大小的联合组装与设计者寡的mRNA的直接细胞质输送

Ruilu Feng1, Mehrnoosh Rafiei1, Kalindu S Fernando1

  • 1Chemical and Biological Engineering Department, The Hong Kong University of Science and Technology, Hong Kong SAR, China. keychau@ust.hk.

Journal of materials chemistry. B
|January 13, 2025
PubMed
概括

携带mRNA的微米尺寸载体绕过细胞内基因组直接进入细胞质中,性能优于纳米粒子和商业试剂. 这种新的方法通过避免 lysosomal 降解来提高核酸输送效率.

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