相关实验视频
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Conducting Respiratory Oscillometry in an Outpatient Setting
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在呼吸衰竭临床试验中西班牙裔患者的代表性:系统性审查
Emily A Harlan1,2,3,4, Kaitlin Malley5, Grecia Quiroga5
1Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI.
Critical care explorations
|January 13, 2025
概括
在2020年之前,在急性缺血性呼吸衰竭 (AHRF) 临床试验中,西班牙裔患者的代表性不足. 在COVID-19期间出现了代表性增加,但语言障碍可能仍然限制了呼吸衰竭研究的入学率.
科学领域:
- 关键护理医学 关键护理医学
- 卫生公平研究 卫生公平研究
- 临床试验多样性临床试验多样性
背景情况:
- 西班牙裔个人占美国人口的很大一部分.
- 患有急性缺血性呼吸衰竭 (AHRF) 的西班牙裔患者面临更高的死亡率.
- 确保临床试验中的多元化代表性对于解决健康差异至关重要.
研究的目的:
- 系统地审查将西班牙裔患者纳入AHRF随机对照试验 (RCT) 的情况.
- 评估语言是西班牙裔患者参加AHRF临床试验的潜在障碍.
主要方法:
- 对AHRF干预措施的RCT进行了系统审查.
- 在控制试验的PubMed,Embase和Cochrane中央注册表中进行了搜索,直到2024年1月.
- 数据提取和选由两位作者独立进行.
主要成果:
- 在包括的94项试验中 (1975-2023年),只有33%的人报告了种族.
- 西班牙裔参与者占报告种族/种族的11.2%,明显低于2020年之前的美国人口.
- 从2020年开始,西班牙裔代表人数显著增加 (27.8%),与COVID-19大流行相吻合.
结论:
- 从历史上看,西班牙裔个人在AHRF试验中代表性不足,从2020年开始,他们得到了更好的包容.
- 排除不说英语的参与者可能会阻碍试验入学.
- 解决语言障碍对于公平参与呼吸衰竭研究至关重要.
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