ZNFX1 作为表观遗传诱导的病原体模仿和炎症体信号传递在癌症中的主调节器

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Updated: Jun 2, 2025

A Chromatin Immunoprecipitation Assay to Identify Novel NFAT2 Target Genes in Chronic Lymphocytic Leukemia
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A Chromatin Immunoprecipitation Assay to Identify Novel NFAT2 Target Genes in Chronic Lymphocytic Leukemia

Published on: December 4, 2018

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Lora Stojanovic1,2, Rachel Abbotts1,2, Kaushelendra Tripathi1,2

  • 1University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.

Cancer research
|January 13, 2025
PubMed
概括

基因甲基转移酶 (DNMT) 和PARP抑制剂对ZNFX1进行上调,ZNFX1是一种触发病原体模仿反应 (PMR) 的蛋白质. 在卵巢癌中,ZNFX1充当瘤抑制剂,可能作为个性化治疗的生物标志物.

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