用His15乙胺修饰的蛋白溶酶的结构:来自老朋友的愉快惊喜

Jose Malanho da Silva1, Jose Lanuza1, Francesco Bruno1

  • 1Department of Chemistry `Ugo Schiff', Università degli Studi di Firenze, Via della Lastruccia 3, 50019 Sesto Fiorentino, Italy.

概括

研究人员通过化学修饰蛋白溶酶 (HEWL) 中的活性N原子. 意想不到的是,修改后的HEWL晶体采用了与标准四角形不同的正方形系统.

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