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口服补充剂和光保护:系统性审查
Nicole Natarelli1, Shaliz Aflatooni1, Kaylee Stankiewicz1
1University of South Florida. Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Journal of medicinal food
|January 13, 2025
概括
饮食补充剂,如多,胡卜素和Polypodium leucotomos显示出光保护作用. 需要进一步的研究来确认最佳剂量,以提高防晒保护.
科学领域:
- 皮肤病学 皮肤病学
- 营养科学 营养科学
- 摄影生物学 摄影生物学
背景情况:
- 营养成分和补充剂在临床前研究中已经证明了光保护作用.
- 评估食补充剂对保护皮肤免受紫外线辐射的有效性至关重要.
研究的目的:
- 系统地审查各种食补充剂对人体光保护作用的研究.
- 为了确定具有最强有力的证据来增强皮肤对紫外线辐射防御的补充剂.
主要方法:
- 从PubMed,Embase和Cochrane数据库中对2023年2月之前发表的人类研究进行系统审查.
- 搜索了使用关键词与食补充剂 (例如,多,胡卜素,Polypodium leucotomos) 和光保护结果 (例如,紫外线保护,UVA,UVB) 相关的研究.
- 包括47项评估一系列补充剂的研究,包括胡卜素,多,Polypodium leucotomos,维生素和脂肪酸.
主要成果:
- 聚醇,基于胡卜素的补充剂和Polypodium leucotomos (PL) 证明了光保护的最强有力的证据.
- 醇补充剂显示剂量依赖性,但对于其他多醇,这种情况并未始终观察到.
- 单独的维生素或辅酶Q补充剂对光保护作用的支持证据最弱.
结论:
- 食补充剂可以提供增强的光保护,特别是对于紫外线敏感的人来说.
- 目前的证据受到小样本大小和研究时间短暂的限制.
- 需要进一步的研究来确定最佳剂量和补充时间,以获得有效的光保护.
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