相关实验视频

Updated: Jun 2, 2025

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
06:17

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

Published on: May 22, 2018

11.8K

奥里塔万辛对hIAPP粉样蛋白形成的作用和机制

Sheng-Nan Wang1, Xin-Yu Li1, Zhong-Xia Lu1

  • 1Key Laboratory of Marine Drugs, Ministry of Education; School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao 266003, China. luxinzhi@ouc.edu.cn.

Journal of materials chemistry. B
|January 13, 2025
PubMed
概括

奥里塔万辛抑制了人类小岛粉样蛋白多 (hIAPP) 粉样蛋白的形成,这是2型糖尿病 (T2D) 发病的一个关键因素. 这一发现为T2D提供了潜在的新疗法策略,通过重新利用现有的抗生素.

更多相关视频

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain10:08

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain

Published on: August 28, 2012

11.8K
Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices04:41

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices

Published on: July 14, 2010

23.1K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.2K