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Updated: Jun 2, 2025

Using a GFP-tagged TMEM184A Construct for Confirmation of Heparin Receptor Identity
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在肝硫酸乙生物合成中GTPases和囊泡适配蛋白的参与:Rab1A,Rab2A和GOLPH3的作用

Maria C Z Meneghetti1, Renan P Cavalheiro1, Edwin A Yates1,2

  • 1Departamento de Bioquímica, Instituto de Farmacologia e Biologia Molecular, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.

The FEBS journal
|January 13, 2025
PubMed
概括

沉默Rab1A和Rab2A通过改变3-O-硫转移酶-5 (3OST5) 的戈尔吉局部化来影响肝硫酸盐 (HS) 的产生. 被Rab2A抑制的细胞表现出补偿性的Rab1A增加,揭示出一种新的HS生物合成调节.

关键词:
在GOLPH3中,我们可以打高尔夫球.拉伯1A 拉伯1A 是一个在 Rab2A 里面.生物合成生物合成肝素硫酸盐是什么 肝素硫酸盐

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