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Updated: Jun 2, 2025

In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
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In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells

Published on: September 23, 2021

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衰老细胞衍生的细胞外囊通过协调免疫监测来抑制癌症复发

Tahereh Ziglari1,2, Nicholas L Calistri3, Jennifer M Finan2

  • 1Department of Otolaryngology - Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon.

Cancer research
|January 13, 2025
PubMed
概括

衰老的瘤细胞释放出细胞外囊泡 (EVs),这些囊泡对于癌细胞的免疫清除和抑制瘤复发至关重要. 这些EV启动炎症反应,招募免疫细胞,并激活T细胞,突出其治疗潜力.

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A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells11:15

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