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Updated: Jun 27, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
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自体主导光学缩患者的临床和结构参数:使用光学一致性断层扫描的横截面研究

Anna Camós-Carreras1, Marc Figueras-Roca, Salut Albà-Arbalat

  • 1Ophthalmology Department (AC-C, MF-R, SA-A, RA, BS-D), Seu Maternitat, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain; Faculty of Medicine and Health Sciences (AC-C, SA-A, BS-D), Universitat de Barcelona, Barcelona, Spain; Fundació Per La Recerca Biomèdica-IDIBAPS (MF-R, SA-A, BS-D), Barcelona, Spain; and Ophthalmology Department (MS-G), Consorci Mar Parc de Salut de Barcelona, Barcelona, Spain.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
|January 13, 2025
PubMed
概括

自体主导视力缩 (ADOA) 与视力丧失和神经损伤有关. 光学连贯断层扫描 (OCT) 揭示了结构性变化,状细胞综合体 (GCC) 显示为监测这种遗传性光神经病变的生物标志物具有前途.

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...