改进PREVENT预测模型,以使用焦虑和抑郁的措施来预测心血管疾病的10年风险
Shinya Nakada1, Paul Welsh2, Carlos Celis-Morales2
1Schools of Health and Wellbeing (Nakada, Pell, Ho), and Cardiovascular and Metabolic Health (Welsh, Celis-Morales), University of Glasgow, Glasgow, UK; Human Performance Laboratory, Education, Physical Activity and Health Research Unit (Celis-Morales), Universidad Católica del Maule, Talca, Chile; Centro de Investigación en Medicina de Altura (CEIMA) (Celis-Morales), Universidad Arturo Prat, Iquique, Chile. 2544363N@student.gla.ac.uk.
在心血管疾病 (CVD) 风险预测模型中添加抑郁症和焦虑症测量结果显示出最小的改善. 这些心理健康因素可能不会显著提高人口层面的心血管疾病风险分类.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 焦虑和抑郁与心血管疾病 (CVD) 有关.
- 现有的心血管疾病风险预测模型可能无法完全捕捉与心理健康状况相关的风险.
研究的目的:
- 评估是否结合焦虑和抑郁症措施可以增强美国心脏协会预测心血管疾病事件风险 (PREVENT) 模型.
- 在心血管疾病风险评估中评估心理健康数据的增量预测价值.
主要方法:
- 利用英国生物库数据 (n=325,815) 进行模型开发和验证.
- 包括抑郁症症状得分和焦虑/抑郁症诊断作为心理健康预测指标.
- 使用C指数,灵敏度,特异性和净重新分类改进的评估预测性改进.
主要成果:
- 除了自我报告的焦虑之外,添加了大多数心理健康指标,导致C指数和特异性略有增加.
- 抑郁症状得分在C指数 (0.005) 和特异性 (0.89%) 中得到了最大的改善.
- 改善在不同性别之间是一致的.
结论:
- 将抑郁和焦虑措施纳入PREVENT模型对在人口层面上进行心血管疾病风险分类几乎没有额外的好处.
- 当前的心理健康评估可能对提高广义心血管疾病风险预测准确性没有必要.
更多相关视频
06:55An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
07:31Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
相关概念视频
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
