功能与健康预期寿命之间的关系:一项历史上的队列研究
Hisayuki Ogura1, Tadashi Toyama2,3, Hikaru Samuta4
1Department of Nephrology and Rheumatology, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, 920-8641, Japan.
BMC nephrology
|January 13, 2025
概括
慢性病 (CKD) 影响预期寿命和医疗保健成本. 低估计的淋巴膜过率 (eGFR) 与更不健康的年龄和更高的医疗费用有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
背景情况:
- 慢性病 (CKD) 显著影响预期寿命,并导致大量的医疗保健费用.
- 需要进行研究来了解CKD,健康预期寿命和它所带来的经济负担之间的关系.
研究的目的:
- 为了检查由估计的膜过率 (eGFR) 定义的CKD与健康预期寿命之间的关联.
- 调查与CKD相关的经济负担,包括医疗和长期护理费用.
主要方法:
- 在日本Hakui市的社区居民成年人使用国家健康保险数据 (2012-2022) 进行了分析.
- 参与者根据基线eGFR水平进行分类.
- 主要终点是治疗水平 (≥2) 或死亡的复合结果,使用Cox比例危险模型进行分析.
主要成果:
- 总共有5,592名参与者被跟踪平均6.4年.
- 与基准组 (eGFR 60-74.9) 相比,在最低的eGFR组 (eGFR < 45) 和最高的eGFR组 (eGFR ≥ 90) 中观察到对主要终点显著更高的风险.
- 较低的eGFR与更长的不健康生命周期以及每年医疗和长期护理费用显著增加相关.
结论:
- 非常低和非常高的eGFR水平都与减少健康预期寿命的风险增加有关.
- 较低的eGFR是医疗和长期护理支出增加的重要预测因素.
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