儿童的奇孔古尼亚感染:临床概况和结局
Korra Dhanunjaya Naik1, C G Delhi Kumar1, Anitha Abimannane1
1Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry 605006, India.
Journal of tropical pediatrics
|January 14, 2025
概括
儿童的 Chikungunya 感染表现不同于成人,常见的症状包括发烧,皮疹,并可能导致严重的并发症,如毛细血管泄漏. 大多数孩子都会康复,但有些人会经历长时间的关节疼痛或严重的后果.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- Chikungunya 病毒感染是一个重大的公共卫生问题.
- 关于儿童群体中 chikungunya 的特定临床特征和结果的数据有限.
- 了解儿科 chikungunya 对于有效的管理和公共卫生策略至关重要.
研究的目的:
- 调查儿童中 chikungunya 感染的临床过程,并发症范围和死亡率.
- 描述小儿病患者中 chikungunya 的人口统计,临床和实验室特征.
- 为了比较儿科奇孔古尼亚的表现与成人报告的表现.
主要方法:
- 结合了回顾性和前性观察性研究设计.
- 纳入标准:年龄在1个月至15岁的儿童,已确诊患有 chikungunya 感染 (IgM ELISA 和 RT-PCR).
- 收集的数据包括人口统计,临床表现,实验室参数,治疗和结果.
主要成果:
- 其中包括58名儿童;发烧,吐和肌痛是常见的症状.
- 皮肤皮疹,肝扩大和贫血是经常观察到的临床症状.
- 急性并发症包括淋巴缺血,低血症,毛细血管泄漏综合征和血栓缺血;发生2例死亡.
结论:
- 儿童的 Chikungunya 经常表现为皮肤和神经症状,与成人表现不同,主要集中在关节痛上.
- 显著比例的儿科病例经历严重的并发症,包括毛细血管泄漏综合征.
- 虽然大多数儿童完全康复,但部分儿童可能会出现长期关节痛或致命的结果,这凸显了需要警的儿科护理的需要.
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