患者报告的COVID-19后状况的结果措施:对仪器和测量特性进行系统审查
Ann-Kristin Baalmann1, Christine Blome2, Nina Stoletzki2
1Institute of Social Medicine and Health Systems Research, Faculty of Medicine, Otto von Guericke University, Magdeburg, Germany.
BMJ open
|January 14, 2025
概括
评估了COVID-19后病情 (PCC) 患者报告的结果措施 (PROMs). 建议使用长期Covid污名度量表 (LCSS),但对其他评估PCC症状和影响的PROMs需要更多的验证.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 患者报告的结果
- 康复医学 康复医学 康复医学
背景情况:
- 后COVID-19状态 (PCC),或长期COVID,是一个重要的公共卫生挑战.
- 通过患者报告的结果指标 (PROM) 评估患者的观点,对于制定有效的管理策略至关重要.
研究的目的:
- 批判性地评估PCC现有的PROM的质量.
- 确定适合未来研究和临床使用的PROM,用于评估长期COVID.
主要方法:
- 使用基于共识的健康测量仪器选择标准 (COSMIN) 方法进行了系统审查.
- 在PubMed和Web of Science进行了搜索,包括关于PCC特定疾病PROM开发和验证的研究.
- 用COSMIN偏差风险检查清单和手册标准评估PROM的方法质量和测量特性.
主要成果:
- 确定了11个PROM,测量功能状态,症状负担,生活质量和耻辱感.
- 长期Covid污名度量表 (LCSS) 显示了足够的内容有效性和内部一致性,因此值得推.
- 大多数PROM存在显著的证据缺口,特别是关于内容有效性,需要进一步的验证研究.
结论:
- 建议使用LCSS来评估COVID-19后疾病研究中的耻辱感.
- 目前,没有PROM具有足够的测量特性来评估PCC症状和影响.
- 进一步验证所有已识别的PROM,特别是关于患者和专家输入的内容有效性的进一步验证是必不可少的.
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