从NHANES的角度来看,LE8得分和外围动脉疾病之间的关系
Zhixian Liu1, Zhibo Zhang2, Tianhua Li3
1Kailuan General Hospital Linxi Hospital, Hebei, China.
VASA. Zeitschrift fur Gefasskrankheiten
|January 14, 2025
概括
使用生命必不可少的8 (LE8) 度量来改善心血管健康与较低的外周动脉疾病 (PAD) 风险有关. 较高的LE8得分显著降低了美国成年人中PAD患病率.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 血管疾病 血管疾病
背景情况:
- 周围动脉疾病 (PAD) 是一种严重的血管疾病.
- 心血管健康 (CVH) 评估对公共健康至关重要.
- 生命的基本8 (LE8) 度量提供了一个全面的CVH评估.
研究的目的:
- 调查美国人口中LE8指标和PAD患病率之间的关联.
- 为了确定更高的心血管健康水平是否有助于预防PAD.
- 为PAD预防策略提供证据.
主要方法:
- 基于人口的前性队列研究,使用国家健康和营养检查调查 (NHANES) 数据 (1999-2004).
- 分析了6076名20岁以上的美国成年人.
- 使用后勤回归模型来评估LE8定义的CVH水平 (低,中等,高) 和PAD患病率之间的关系,调整为共变量.
主要成果:
- 在研究参与者中,PAD的总体患病率为6.9%.
- 与低CVH患者相比,中度CVH患者的PAD风险降低了34% (OR:0.66,95%CI:0.53至0.82).
- 患有高CVH的参与者表现出PAD风险降低了62% (OR:0.38,95%CI:0.25-0.58).
结论:
- 根据LE8指标测量,较低的心血管健康与增加的外周动脉疾病风险显著相关.
- 促进更高的心血管健康水平可能是预防PAD的关键策略.
- 这些发现凸显了LE8指标在预防血管疾病的公共卫生倡议中的重要性.
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