呼吸道共囊病毒 (RSV) 诱导的自身免疫血液溶解性贫血呈现为昏迷:一个病例报告
1Emergency Medicine, University Hospitals St. John Medical Center, Westlake, USA.
Cureus
|January 14, 2025
概括
呼吸道同胞性病毒 (RSV) 可以引发热性自身免疫血液溶解性贫血 (AIHA),这是免疫系统攻击红细胞的状况. 这一案例强调了RSV是AIHA的原因,需要及时诊断和管理.
科学领域:
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 自身免疫血液溶解性贫血 (AIHA) 涉及免疫媒介红细胞的破坏.
- 温暖的AIHA的特征在于在体温下针对红细胞的抗体.
- 症状性贫血发生在血液溶解超过骨髓补偿能力时.
研究的目的:
- 报告一个由呼吸道同胞病毒 (RSV) 引起的温暖AIHA病例.
- 为了突出自身免疫血液溶解性贫血的一个不寻常的触发因素.
- 强调在AIHA病因学中考虑病毒感染的重要性.
主要方法:
- 病例报告详细介绍了一名患有同性情节的患者.
- 对贫血和血液溶解进行临床评估和诊断工作.
- 识别呼吸道同胞病毒感染和温暖的AIHA.
主要成果:
- 由于严重的贫血,该患者出现了综合性发作.
- 诊断证实了温暖的自身免疫血液溶解性贫血 (AIHA).
- 呼吸道同胞性病毒 (RSV) 感染被确定为AIHA的可能触发因素.
结论:
- 呼吸道同胞性病毒 (RSV) 可以诱导温暖的自身免疫血液溶解性贫血 (AIHA).
- 这一案例强调了在AIHA中调查病毒触发因子的必要性.
- 及时诊断和管理对于病毒诱导的AIHA患者至关重要.
更多相关视频
09:14An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
Published on: January 26, 2019
10.7K
09:01An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
7.9K
相关概念视频
Rheumatic Heart Disease I: Introduction
355
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
355
Myocarditis I: Introduction
287
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
287
Acute Respiratory Failure-I
745
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
745
Acute Respiratory Failure-V
384
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
384
Acute Respiratory Failure-II
941
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
941
Acute Respiratory Failure-III
679
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
679
