在社区中血管衰老的表现和高血压
Guillermo A Alanis1, Pierre Boutouyrie2,3, Mouad Abouqateb1
1Université Paris Cité, INSERM U970, Paris Cardiovascular Research Centre, Team Integrative epidemiology of cardiovascular diseases, Paris, France.
American journal of preventive cardiology
|January 14, 2025
概括
血管衰老的表现如动脉样硬化和动脉样硬化与现有和新出现的高血压病例有关. 这项研究强调了与高血压相关的血管衰老的关键指标.
科学领域:
- 心血管医学 心血管医学
- 老年学是一门学科.
- 公共卫生 公共卫生
背景情况:
- 血管衰老 (VA) 涉及随着时间的推移,血管的生理变化.
- 高血压是心血管疾病的主要危险因素.
- 了解VA和高血压之间的联系对于预防和管理至关重要.
研究的目的:
- 调查血管衰老和高血压的联合表现之间的联系.
- 识别血管衰老的模式及其与流行和发病高血压的关系.
主要方法:
- 利用了来自巴黎前性研究III (10,157名参与者) 的数据.
- 通过声动脉的回声跟踪来评估血管衰老.
- 采用集群分析和后勤回归来确定与高血压的关联.
主要成果:
- 确定了VA的三个集群:健康 (HVA),动脉样硬化 (ART) 和动脉样硬化 (ATH).
- ART和ATH集群与患高血压有显著的相关性 (aOR分别为3.94和2.69).
- 在10年的随访期间,ART和ATH两种都与事件高血压有关 (aOR分别为1.34和1.70).
结论:
- 血管衰老的表现,特别是动脉动脉样硬化和动脉样硬化增加,与流行和发生的高血压有关.
- 这些发现强调了在高血压风险分层中评估血管健康的重要性.
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