Jove
Visualize
联系我们

相关概念视频

Structure and Function of Erythrocytes01:29

Structure and Function of Erythrocytes

1.7K
There are between 4.2 and 6 million erythrocytes, also known as red blood cells, in every microliter of blood. These cells are small, flattened biconcave discs with centers that are depressed.
The erythrocyte plasma membrane is associated with proteins such as spectrin, which forms a flexible cytoplasmic meshwork. This meshwork allows erythrocytes to twist, turn, become cup-shaped, and regain their biconcave shape as they pass through narrow capillaries. Additionally, erythrocytes can form...
1.7K
Protein and Protein Structure02:15

Protein and Protein Structure

78.2K
Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
78.2K
Overview of Hematopoiesis01:20

Overview of Hematopoiesis

3.7K
Hematopoiesis, or blood cell production, is a vital biological process that begins early in embryonic development and continues throughout life. This process generates the various types of cells found in blood, including red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs).
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
3.7K
Production of Formed Elements01:34

Production of Formed Elements

1.3K
Hemangioblasts are multipotent stem cells originating from the mesoderm. They give rise to hematopoietic stem cells (HSCs), which undergo hematopoiesis to produce all the formed elements of blood. This process is regulated by a complex network of hematopoietic growth factors, including transcription factors, growth factors, and cytokines. These factors stimulate the HSCs to divide and differentiate, though some HSCs remain undifferentiated to maintain a self-renewing pool.
Most HSCs commit to...
1.3K
Structural Protein Function01:56

Structural Protein Function

27.4K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
27.4K
Cell Diversity01:13

Cell Diversity

3.0K
The concept of a cell started with microscopic observations of dead cork tissue by Robert Hooke in 1665. Hooke coined the term "cell" based on the resemblance of the small subdivisions in the cork to the rooms that monks inhabited, called cells. About ten years later, Antonie van Leeuwenhoek became the first person to observe the living and moving cells under a microscope. In the century that followed, the theory that cells represented the basic unit of life developed.
Multicellular...
3.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Stabilizing in-transition phases of superlattices through shape control of silver nanocrystals.

Science (New York, N.Y.)·2026
Same author

Exploring entropy landscapes using hard particle Monte Carlo metadynamics.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Intermetallic nanoassemblies potentiate systemic STING activation.

Science (New York, N.Y.)·2026
Same author

Quantifying local point-group-symmetry order in complex particle systems.

The Journal of chemical physics·2026
Same author

Engineering low-symmetry colloidal crystals with optical anisotropies.

Science advances·2026
Same author

Using particle shape to control defects in colloidal crystals on spherical interfaces.

Soft matter·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jun 2, 2025

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
09:12

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

Published on: January 12, 2018

14.5K

红血细胞的形状依赖的结构顺序

Logan D Piegols1, Tobias Dwyer1, Sharon C Glotzer1,2

  • 1Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States.

Langmuir : the ACS journal of surfaces and colloids
|January 14, 2025
PubMed
概括

红细胞的形状显著影响它们在接口上的排列. 球形细胞比圆盘形细胞具有更大的秩序和聚类,为疾病检测提供了潜在的潜力.

科学领域:

  • 生物物理学的生物物理.
  • 细胞生物学 细胞生物学
  • 材料科学 材料科学 材料科学

背景情况:

  • 红细胞 (RBC) 形态对于功能至关重要.
  • 遗传性球细胞症涉及异常的红细胞形状.
  • 了解红细胞在接口上的排序,可以提供疾病的洞察力.

研究的目的:

  • 研究RBC形状对它们在水空气界面上的排序的影响.
  • 使用人工硬化和球状红细胞建模遗传球细胞分裂.
  • 为了将结构变化与红细胞形状和疾病指标相关联.

主要方法:

  • 使用人工红细胞模型 (硬化和球状细胞).
  • 分析水空界面上的RBC安排.
  • 量化辐射分布函数,局部键序和细胞聚类.

主要成果:

  • 球形红细胞与圆盘形红细胞相比,显示出增强的远程顺序.
  • 刚性稍微增加了细胞间的距离,特别是球形细胞.
  • 球状细胞聚类和局部六合键顺序随着球状细胞分数的增加而出现.

结论:

更多相关视频

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation
10:27

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation

Published on: June 4, 2015

11.8K
Immunostaining-Based Detection of Dynamic Alterations in Red Blood Cell Proteins
10:07

Immunostaining-Based Detection of Dynamic Alterations in Red Blood Cell Proteins

Published on: March 17, 2023

1.9K

相关实验视频

Last Updated: Jun 2, 2025

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
09:12

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

Published on: January 12, 2018

14.5K
Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation
10:27

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation

Published on: June 4, 2015

11.8K
Immunostaining-Based Detection of Dynamic Alterations in Red Blood Cell Proteins
10:07

Immunostaining-Based Detection of Dynamic Alterations in Red Blood Cell Proteins

Published on: March 17, 2023

1.9K
  • 接口处的红细胞结构主要是由细胞形状决定的.
  • 形状依赖的结构变化可以作为红细胞疾病的生物标志物.
  • 这项研究为开发红细胞病的诊断工具提供了基础.