在患有神经性膀的儿童中,增强细胞形成术后的代谢后果和管状功能
Jei-Wen Chang1,2,3, Hui-Hsin Yang2,4, Tzu-Ching Lin1,2
1Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Journal of the Chinese Medical Association : JCMA
|January 14, 2025
概括
在儿童中,增强细胞形成术 (AC) 是安全的,对代谢概况没有显著影响. 虽然低磁性尿是常见的,但在这项研究中,它与尿病没有相关.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 代谢医学是一种代谢医学.
背景情况:
- 有限的研究存在于管功能变化后的增加细胞形成术 (AC) 的管功能变化.
- 这项研究涉及脏结果,代谢后果和AC后的24小时尿液化学.
- 调查代谢变化及其与AC后尿病的相关性至关重要.
研究的目的:
- 在AC后的儿童中调查代谢障碍和管功能.
- 评估24小时尿液化学及其与AC后尿病的关系.
- 评估代谢并发症的患病率和AC后的状况.
主要方法:
- 在儿科AC患者中分析了血清生物化学,血液气体和24小时尿路代谢概况.
- 评估结果包括代谢并发症,管状功能和状况.
- 研究了尿路代谢参数与尿病之间的关联.
主要成果:
- 研究了25名患者,平均随访时间为13.8年;24小时尿液低磁石尿是常见的 (72.0%).
- 没有发现血清电解质或的显著异常.
- 尿发生在44.0%的患者中,但没有特定的尿路代谢参数与其发展有关.
结论:
- 增强细胞形成术 (AC) 对儿童来说是安全的,没有显著的代谢特征影响.
- 24小时尿中的,尿酸,和与的比率与尿症无关.
- 需要进一步研究管功能的纵向变化和AC后的状况.
相关概念视频
Renal Tubule and Collecting Duct
758
The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
758
The Micturition Reflex
416
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
416
Disorders of the Urinary System
230
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
230
Physiology of Urine Formation
2.9K
Urine formation is an essential function of the human body. It plays a critical role in maintaining homeostasis by regulating the volume and composition of body fluids. The kidneys, the primary organs involved in this process, filter blood to remove waste products and excess substances, ultimately producing urine.
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
2.9K


