美国成年女性心脏代谢指数和膀过度活跃之间的关联:一个横截面研究
1School of Mathematics and Computer Science, Hanjiang Normal University, Shiyan, Hubei, China.
PloS one
|January 14, 2025
概括
较高的心脏代谢指数 (CMI) 与女性过度活性膀 (OAB) 风险增加有关. 这表明代谢健康可能会影响膀功能,提供新的预防策略.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 过度活跃的膀 (OAB) 显著影响女性的生活质量.
- 心脏代谢指数 (CMI) 是一种新兴的代谢风险指标.
研究的目的:
- 调查成年女性中CMI和OAB之间的关联.
- 探索代谢健康和膀功能障碍之间的潜在联系.
主要方法:
- 对来自6323名女性的NHANES数据 (2007-2018) 的横截面分析.
- CMI是从腰与身高的比例,甘油三和高密度胆固醇计算出来的.
- 使用OABSS评估OAB;通过后勤回归和GAMs分析关联.
主要成果:
- 在女性中CMI和OAB患病率之间发现了显著的积极关联 (OR=1.46).
- 与最低四分位数相比,CMI最高四分位数的女性患上OAB的可能性增加了70%.
- 这种关联是线性的,在没有高血压的20-50岁女性中更强烈.
结论:
- 较高的CMI与女性OAB的更高患病率显著相关.
- 研究结果表明CMI是OAB风险的潜在标志物,特别是在年轻的非高血压女性中.
- 这项研究为代谢风险管理和OAB预防策略提供了洞察力.
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