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Updated: Jun 2, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

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在Silico设计和分子动力学分析中,imidazole衍生物作为选择性环氧化酶-2抑制剂

Mohamed J Saadh1, Hanan Hassan Ahmed2, Radhwan Abdul Kareem3

  • 1Faculty of Pharmacy, Middle East University, Amman, 11831, Jordan.

Computational biology and chemistry
|January 14, 2025
PubMed
概括

新型伊米达衍生物显示出作为循环氧化酶-2 (COX-2) 抑制剂的前景. 化合物5b表现出最好的结合亲和力和有利的药理动力学特性,表明其在抗炎药物发现中进一步发展的潜力.

关键词:
这是一种COX酶.药物发现 药物发现炎症 炎症是一种炎症.分子动态模拟分子动态模拟

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