通过系统的结构优化,发现了蛋白质溶解稳定的单细胞运动抑制因子

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Yajing Ji1, Yuan Gao2, Xiang Li3

  • 1Institute of Translational Medicine, Shanghai University, Shanghai, 200444, China; School of Medicine, Shanghai University, Shanghai, 200444, China.

European journal of medicinal chemistry
|January 14, 2025
PubMed
概括

研究人员优化了抗炎性MLIF用于骨关节炎治疗. 一个修改后的版本,MLIF 30,在小鼠的软骨炎症和损伤减少方面显示出更好的稳定性和有效性.

关键词:
这是一种抗炎症药物.单细胞运动抑制因子骨关节炎是一种骨关节炎.蛋白质溶解稳定性 蛋白质溶解稳定性结构修改是指结构的修改.

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