辅助生殖产生的双胞胎的新生儿后果,与自然出生的双胞胎相比
Lin Lin1, Ting Yao2, Qiuping Liao1
1Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China.
Medicine
|January 14, 2025
概括
辅助生殖技术 (ART) 可能对双胞胎胎的生长产生保护作用,降低低出生体重,早产和子宫内生长限制的风险. 然而,与多胎妊娠相关的风险仍然存在.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿医学 新生儿医学
- 生殖医学 生殖医学
背景情况:
- 辅助生殖技术 (ART) 的使用正在增加,导致更多的双胞胎怀孕.
- 了解ART对双胞胎新生儿结局的影响至关重要.
研究的目的:
- 评估ART对双胞胎怀孕中新生儿结局的影响.
- 为了比较ART怀孕和自然怀孕的双胞胎之间的结果.
主要方法:
- 对1270次双胞胎交付 (2019-2021) 的回顾性分析.
- 在ART和自然受孕双胞胎之间对新生儿结局 (LBW,IUGR,早产,Apgar分数,NICU入院) 的比较.
- 对混因素进行调整后的物流回归分析.
主要成果:
- 通过人工智能治疗怀孕的双胞胎的出生体重低 (LBW) 的几率显著降低 (aOR 0.57)
- 通过人工智能治疗怀孕的双胞胎早产率降低 (aOR 0.71) 和子宫内生长限制 (IUGR) (aOR 0.21).
- 其他新生儿结局,包括Apgar分数和NICU入院,在各组之间是可比的.
结论:
- ART可能对双胞胎胎的生长有保护作用,降低了LBW,早产和IUGR的发生率.
- 虽然ART似乎对双胞胎的特定新生儿结果有益,但多胎妊娠的一般风险仍然存在.
- 需要进一步的研究来阐明机制和长期影响.
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