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Updated: Jun 2, 2025

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衰老期间的中粒体不活化可以在人类细胞中得到挽救

Sweta Sikder1, Songjoon Baek1, Truman McNeil2

  • 1Center for Cancer Research, National Cancer Institute/NIH, Bethesda, MD 20892, USA.

Molecular cell
|January 14, 2025
PubMed
概括

由于表观遗传变化,衰老细胞会失去像CENP-A这样的中心蛋白质. 抑制p53和LSD1/KDM1A通过恢复中心膜功能,使这些细胞复苏.

关键词:
这就是CENP-A.老化的老化 衰老的老化癌症 癌症 癌症 癌症 癌症中心的中心 (centromere)在这种情况下,染色染色素基因组的不稳定性基因组脱甲基酶 (Histone Demethylase) 是一种基因组脱甲基酶.非编码转录的转录.在 p53 里,p53 是一个 p53 的类型.衰老是一种老化.

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