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评估潜在药物相关症状的患者报告工具:系统性审查
Abebe Basazn Mekuria1, Henok Getachew Tegegn2, Andre Q Andrade1
1Quality Use of Medicines and Pharmacy Research Centre, UniSA Clinical and Health Sciences, University of South Australia, Adelaide, 5001, Australia.
Research in social & administrative pharmacy : RSAP
|January 14, 2025
概括
这次审查确定并评估了与药物相关的症状评估工具. 对于独立的老年人来说,建议使用PHARmacotherapeutical Symptom Evaluation-20 (PHASE-20),而PHASE-proxy则适用于痴呆症患者.
科学领域:
- 药理学和老年医学 药理学和老年医学
- 健康 结果 研究 研究 结果
- 临床评估工具 临床评估工具
背景情况:
- 医疗保健专业人员利用与药物相关的症状评估工具来识别潜在的不良药物事件.
- 进行了系统审查,以评估这些工具的测量特性.
研究的目的:
- 系统地识别和评估与药物相关的症状评估工具的测量特性.
- 确定现有工具是否适合在不同老年人群中临床使用.
主要方法:
- 在主要数据库 (Ovid Medline,Embase,PsychInfo,SCOPUS) 进行了全面的系统搜索,截至2024年3月.
- 包括描述药物相关症状工具的开发或测量属性的研究.
- 方法质量和测量属性使用COSMIN检查清单进行评估.
主要成果:
- 在11项研究中确定了9种独特的工具,所有这些研究都显示出足够的内容有效性.
- 在PHARmacotherapeutical Symptom Evaluation-20 (PHASE-20) 中,在内部一致性,构造有效性和可靠性方面显示出足够到非常好的质量.
- 此外,PHASE-proxy的质量也显示为足够到非常好,在标准有效性,结构有效性,内部一致性和可靠性方面表现出色.
结论:
- 阶段20适用于评估独立运作的老年人的药物相关症状.
- 对于老年痴呆症或在养老院环境中遇到沟通困难的老年人来说,建议使用PHASE-proxy.
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