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Updated: Jun 2, 2025

A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
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A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta

Published on: September 27, 2017

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与出生体重的罕见变异关联确定了参与脂肪组织调节,胎盘功能和胰岛素样生长因子信号传递的基因

Katherine A Kentistou1, Brandon E M Lim2, Lena R Kaisinger1

  • 1MRC Epidemiology Unit, Box 285 Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.

Nature communications
|January 14, 2025
PubMed
概括

罕见的遗传变异显著影响人类的出生体重,影响胎儿生长和长期健康. 这项研究确定了参与脂肪组织调节和胎盘功能的关键基因,提供了新的生物学见解.

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