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Updated: Jun 2, 2025

Saccharomyces cerevisiae Metabolic Labeling with 4-thiouracil and the Quantification of Newly Synthesized mRNA As a Proxy for RNA Polymerase II Activity
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Published on: October 22, 2018

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转录激活的单分子分析:SAGA联合激活剂招募的动态

Jongcheol Jeon1, Larry J Friedman2, Daniel H Zhou2

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.

Nature structural & molecular biology
|January 14, 2025
PubMed
概括

转录激活剂招募诸如Spt-Ada-Gcn5乙转移酶 (SAGA) 复合体之类的联合激活剂. 单分子显微镜揭示了激活剂显著增加SAGA.

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