在预测结果的创伤复苏期间的电离水平 - - 一项前性队列研究
Ramesh Vaidyanathan1, Preksha Rani1, Shrikanth Manwatkar1
1Division of Trauma Surgery and Critical Care, Jai Prakash Narayan Apex Trauma Center, All India Institute of Medical Sciences [AIIMS], Room 217 Second Floor, New Delhi, India.
概括
创伤引起的低血症 (低电离) 在受伤患者中很常见. 这种情况显著增加了对输血的需求,并与较高的死亡率有关.
科学领域:
- 创伤复苏的复苏治疗方法
- 关键护理医学 关键护理医学
- 紧急医疗 紧急医疗
背景情况:
- 出血是可预防的创伤死亡的主要原因,由致命的三位一体 (酸,低温,凝血病) 加剧.
- 创伤引起的低血症对出血结果的具体影响仍然不清楚.
- 电离水平对患者的结果至关重要,在创伤复苏期间需要早期评估.
研究的目的:
- 为了前性地分析电离水平在创伤复苏中的作用.
- 为了确定电离水平,输血需求和急性受伤患者的死亡率之间的关联.
主要方法:
- 一项前性研究涉及200名急性受伤的出血患者,他们被送往印度一级创伤中心.
- 离子水平在抵达时被测量,在6小时后,在受伤后的第二天.
- 收集了血液输血,人口统计和住院细节的数据,并分析了与低血症和死亡率的关联.
主要成果:
- 72.5%的分析患者在急诊室入院时出现低血症.
- 电离性低血症与需要输血的需求有显著的关联 (p < 0.01).
- 电离性低血与死亡率的增加显著相关 (p = 0.0085),并且在单变量和多变量分析中是死亡率的预测指标.
结论:
- 电离性低血症在急性受伤患者中非常普遍.
- 住院时的创伤诱导的低血症与更大的血液输血需求有关.
- 入院低血症与创伤后的死亡率增加有关.
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