全免疫性炎症值与成年人肺部健康的关联
Ya Lin1, Xiao Lin1, Chufan Ren2
1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
BMC pulmonary medicine
|January 14, 2025
概括
较高的全免疫炎症值 (PIV) 与咳和等呼吸道症状增加以及肺功能降低有关. 监测PIV可能有助于评估炎症和管理肺部健康.
科学领域:
- 肺部医学 肺部医学
- 炎症生物标志物 炎症生物标志物
- 公共卫生 公共卫生
背景情况:
- 肺部健康与全身炎症密切相关.
- 全免疫炎症值 (PIV) 是系统性炎症和疾病预后的潜在生物标志物.
- 了解PIV在呼吸系统健康中的作用至关重要.
研究的目的:
- 为了调查PIV和呼吸系统症状之间的关联.
- 探索PIV和诊断的呼吸道疾病之间的关系.
- 检查PIV对肺功能参数的影响.
主要方法:
- 使用NHANES数据进行横截面研究 (n=6,263).
- 使用受限立方线模型,加权线性/逻辑回归和趋势测试.
- 进行了子组和相互作用分析以完善发现.
主要成果:
- 在PIV和肺部健康之间发现了负相关性.
- 增加PIV与更高的咳和的发病率相关 (OR 1.02).
- 较高的PIV与FEV1和FVC降低以及PIV四分位数中的肺功能下降有关.
结论:
- PIV显示了与呼吸系统症状,疾病和肺功能的潜在关联.
- PIV监测可以提供有关炎症状况的见解.
- 结果可能会为呼吸系统健康管理的临床策略提供信息.
相关概念视频
01:47Lung Capacity
49.3K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
49.3K
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K
01:30Pneumonia III: Complications and Assessment
153
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
153
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:30Pneumonia I: Introduction
205
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
205
01:27Psychoneuroimmunology: Cardiovascular Disease
25
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
25