跨体磁性刺激脉冲间隔不影响皮质脊髓刺激能力双臂在次最大同位数肘部曲期间
David H Imeson1, Lea Gerditschke1, Liana E Brown1,2
1Department of Kinesiology, Trent University, Peterborough, ON, Canada.
The European journal of neuroscience
|January 14, 2025
概括
脉冲间隔 (IPI) 不会影响活动肌肉中的跨磁刺激 (TMS) 反应. 然而,动力唤起的潜在幅度可能会随着在活跃收缩期间的持续刺激而减少.
科学领域:
- 神经科学是一个神经科学.
- 人体生理学 人体生理学
- 发动机控制器的控制器
背景情况:
- 脉冲间隔 (IPI) 持续时间是影响静止肌肉跨磁刺激 (TMS) 反应的已知因素.
- 在活跃肌肉收缩期间IPI对TMS反应的影响不太清楚,这在研究中构成潜在的混变量.
研究的目的:
- 调查IPI与活跃肌肉中的皮质脊髓刺激性之间的关系.
- 为了确定IPI是否会影响在次最大同位方肘部曲过程中引发的运动电位 (MEP).
主要方法:
- 参与者进行了亚最大的同度肘部曲 (10%的最大自愿收缩).
- 经磁刺激 (TMS) 用于在双肩和三腕中引起运动唤起潜能 (MEP).
- 五种刺激的TMS列车在不同的IPI (4,6,8,10,12,14秒) 交付.
主要成果:
- IPI对双肩或三腕的MEP幅度没有显著的影响.
- 当MEP幅度正常化为刺激前的肌肉活动时,在对双肩进行连续刺激时,其幅度呈现逐渐下降 (p < 0.05).
结论:
- 在涉及活跃肌肉收缩的TMS研究中,IPI不太可能是混变量.
- 研究人员在比较随时间推移的反应时,应考虑持续刺激的MEP幅度的潜在下降.
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