淋巴瘤妇女的生育保护咨询和实践:一项回顾性研究
Mariola Hernández Martínez1, César Lizán Tudela1,2, Blanca Carreras Gamón1,2
1Department of Pediatrics, Obstetrics and Gynecology, Universitat de Valencia, Valencia, Spain.
概括
对于淋巴瘤妇女来说,尽管有改善,但生育保护咨询和利用率仍然很低. 需要更多的努力,以确保所有生育年龄的患者在化疗前获得这一关键信息.
科学领域:
- 在瘤学瘤学.
- 生殖医学 生殖医学
- 血液学 血液学 血液学
背景情况:
- 对于被诊断为淋巴瘤的妇女的生育能力保护,研究有限.
- 本研究通过评估信息接收和使用生育保存方法来解决这一差距.
研究的目的:
- 评估在被诊断为淋巴瘤的妇女中接受生育保护咨询和干预措施的情况.
- 确定影响收到生育保护信息的因素.
主要方法:
- 对霍奇金淋巴瘤和非霍奇金淋巴瘤患者 (2000-2018年) 的回顾性单中心研究.
- 对电子医疗记录进行查,以获得生育保护咨询,干预措施,产科结果和更年期的开始.
- 后续工作至2023年12月.
主要成果:
- 在≤45岁的患者中,13/36 (36.1%) 接受了咨询,在无胎儿,年轻 (≤35岁) 和最近诊断 (2015-2018) 组中更多.
- 8名妇女接受了生育保护 (卵巢皮层冷保存或卵细胞玻璃化).
- 10/36 (27.8%) 有活产;15/43 (34.9%) 在化疗后经历了异常流产.
结论:
- 淋巴瘤患者的生育保育咨询率低于最佳水平,尽管有所改善.
- 需要采取进一步的举措,以确保所有患有淋巴瘤的生育年龄妇女及时接受生育保护咨询.
- 该研究强调,需要更好地将生殖健康讨论纳入淋巴瘤护理途径.
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