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Updated: Jun 2, 2025

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
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Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks

Published on: September 25, 2021

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伊斯卡齐姆:对零膨胀微生物组数据的综合统计相关性分析

Zhe Fan1,2, Jiali Lv1,2, Shuai Zhang1,2

  • 1Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.

Heliyon
|January 15, 2025
PubMed
概括

分析肠道微生物组和代谢组数据是发现疾病生物标志物的关键. ISCAZIM改进了零膨胀微生物组数据的关联分析,增强了多omics集成和生物标志物发现.

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相关概念视频

Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
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Biostatistics: Overview01:20

Biostatistics: Overview

Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...
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Correlation of Experimental Data01:23

Correlation of Experimental Data

Dimensional analysis simplifies complex physical problems and guides experimental investigations, but it does not provide complete solutions. It identifies the dimensionless groups that influence a phenomenon, but experimental data is needed to establish the specific relationships and validate theoretical predictions.
For example, a spherical particle moving through a viscous fluid experiences drag. Dimensional analysis shows that the drag force depends on the particle's diameter, velocity,...
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Statistical Analysis: Overview01:11

Statistical Analysis: Overview

When we take repeated measurements on the same or replicated samples, we will observe inconsistencies in the magnitude. These inconsistencies are called errors. To categorize and characterize these results and their errors, the researcher can use statistical analysis to determine the quality of the measurements and/or suitability of the methods.
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Wilcoxon Signed-Ranks Test for Median of Single Population

The Wilcoxon signed-rank test for the median of a single population is a nonparametric test used to evaluate whether the median of a population differs from a specified value. Unlike parametric tests, it does not require data to follow a normal distribution, making it suitable for non-normal or small samples. The test begins by calculating the difference (d) between each observation and the hypothesized median. The absolute values of these differences are ranked in ascending order, with ties...
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Coefficient of Correlation01:12

Coefficient of Correlation

The correlation coefficient, r, developed by Karl Pearson in the early 1900s, is numerical and provides a measure of strength and direction of the linear association between the independent variable x and the dependent variable y.
If you suspect a linear relationship between x and y, then r can measure how strong the linear relationship is.
What the VALUE of r tells us:
The value of r is always between –1 and +1: –1 ≤ r ≤ 1.
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