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Updated: Jun 2, 2025

Efficient Differentiation of Pluripotent Stem Cells to NKX6-1+ Pancreatic Progenitors
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在胰腺β细胞功能中的长非编码RNAPax6os1/PAX6-AS1的作用

Livia Lopez-Noriega1, Rebecca Callingham1, Aida Martinez-Sánchez1

  • 1Section of Cell Biology and Functional Genomics, Department of Medicine, Endocrinology and Metabolism, Imperial College London, London, UK.

iScience
|January 15, 2025
PubMed
概括

一种新型的长非编码RNA,Pax6os1/PAX6-AS1,在2型糖尿病和高葡萄糖条件下被上调. 它的沉默可以改善β细胞的功能,特别是在人类细胞中.

关键词:
细胞生物学 细胞生物学细胞生理学 细胞生理学分子生物学分子生物学

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