外来污染物准大脑健康
Uma Agarwal1, Arzoo Pannu2, Rajiv Kumar Tonk1
1Department of Pharmaceutical Chemistry, Delhi Pharmaceutical Sciences & Research University, Delhi, 110017, India.
CNS & neurological disorders drug targets
|January 15, 2025
概括
环境污染物与神经退行性疾病和精神健康状况有关. 了解传播途径对于预防神经毒性和保护全球大脑健康至关重要.
科学领域:
- 神经科学是一个神经科学.
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
背景情况:
- 神经退行性疾病和精神健康状况通常与接触不良物质,即污染物有关.
- 这些污染物,无论是概念的还是物理的,都会破坏大脑的功能,导致诸如痴呆症,焦虑症和抑郁症等疾病.
研究的目的:
- 研究环境污染物与神经退行性疾病的发展之间的复杂联系.
- 检查传播途径,分类和与最小化脑健康污染风险相关的挑战.
主要方法:
- 使用PubMed和Scopus进行了全面的文献搜索,重点关注到2024年发表的研究.
- 研究的选择是基于对环境污染物与大脑健康之间的关系的检查,重点是传播途径和神经结果.
主要成果:
- 环境污染物可以通过鼻腔,肠道和听觉通道突破血脑屏障 (BBB).
- 污染物暴露可以触发有害的神经生理过程,导致广泛的神经疾病,包括阿尔茨海默病,帕金森病和自闭症谱系障碍.
结论:
- 迫切需要提高全球意识和政策干预,以减轻环境污染物对大脑健康的不利影响.
- 预防措施至关重要,特别是在新兴国家,以解决神经毒性的长期后果.
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