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Updated: Jun 2, 2025

Novel RNA-Binding Proteins Isolation by the RaPID Methodology
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定量蛋白质学确定Profilin-1是一种伪尿素结合蛋白

Songbo Wei1, Xiaoxia Dai1, Jun Yuan1

  • 1Department of Chemistry, University of California, Riverside, California 92521-0403, United States.

Journal of the American Chemical Society
|January 15, 2025
PubMed
概括

个人蛋白-1 (PFN1) 直接结合含 ψ 尿素 (Ψ) 的 RNA,显示其作为 Ψ 读者蛋白的作用. 这种相互作用对于调节mRNA稳定性和翻译,特别是TPI1基因至关重要.

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Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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