海藻衍生的蛋白质和:制备,虚拟查,促进健康的效果和工业应用
Lu Wang1,2, Lang Wang1, Xiaoze Liu1
1School of Food Science and Engineering, Hainan University, Haikou, P.R. China.
Critical reviews in food science and nutrition
|January 15, 2025
概括
海藻蛋白和提供了许多健康益处和工业应用. 酶解水和虚拟选是制备和识别这些功能性化合物的关键方法.
科学领域:
- 海洋生物技术 海洋生物技术
- 食品科学 食品科学 食品科学
- 生物化学 生化学
背景情况:
- 海藻是丰富的蛋白质来源,包括水解剂,生物活性, phycobiliproteins 和 lectins.
- 这些化合物表现出多样化的生物活性,在补充剂,功能性食品和制药中具有潜在的应用.
研究的目的:
- 审查海藻衍生的功能性的制备方法和虚拟选策略.
- 阐明它们的生物活动,作用机制和工业应用.
主要方法:
- 酶性水解被认为是最有效的制备方法.
- 计算虚拟选被强调为评估的有价值策略.
主要成果:
- 海藻蛋白和具有显著的健康益处,包括抗糖尿病,抗高血压,抗炎症,抗肥胖,抗癌和抗微生物活性.
- 具有芳香/疏水氨基酸的低分子量对生物活性至关重要.
- 这些化合物显示出在食品,药品和食品防腐剂中的广泛使用潜力.
结论:
- 海藻衍生的蛋白质和是有前途的功能成分,具有多样化的生物活性.
- 有效的准备和选方法对于利用它们的潜力至关重要.
- 它们为促进健康的产品和工业应用提供了一个可持续的来源,潜在的副作用较少.
相关概念视频
01:31Hybridoma Technology
Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...
01:30Production of Pharmaceuticals
Industrial insulin production uses genetically engineered E. coli expressing a proinsulin gene controlled by a tryptophan promoter and containing a methionine linker for later cleavage. The cells also carry ampicillin resistance for selective growth. Seed cultures are stored at −80 °C and production begins by thawing a small amount to inoculate starter cultures, which are progressively scaled to a 50,000-L bioreactor. In the bioreactor, E. coli grow in nutrient-rich media under sterile, tightly...