在高负荷的异常病态输出管道中,右心室亚临床功能障碍早发性心室收缩人口
Dicky Armein Hanafy1, Putri Reno Indrisia2, Amiliana Mardiani Soesanto2
1Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. drdhanafy@yahoo.de.
概括
早期心室收缩 (PVC) 的成功切除可以改善右心室 (RV) 功能,特别是在具有先前RV亚临床功能障碍的患者中. 较高的PVC负荷和更长的QRS持续时间预测RV功能障碍.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 过早心室收缩 (PVC) 对右心室 (RV) 功能的影响尚未得到充分证实.
- 由PVCs引起的左心室 (LV) 功能障碍被称为PVC诱导的心肌病 (PIC),PVC抑制可以改善LV功能.
- 对微妙的RV亚临床功能障碍的PVC剥离的影响需要进一步研究.
研究的目的:
- 了解 PVC 剥离后 RV 功能参数的变化.
- 在患有异常出流管PVC的患者中确定RV功能障碍的预测因素.
- 评估PVC剥离在改善RV功能的有效性.
主要方法:
- 包括斑点跟踪在内的心声扫描被用于评估42名患有症状异常外流通道PVC的患者的RV功能.
- 测量是在成功切除PVC前和一个月后进行的.
- 统计分析发现了PVC负担,QRS持续时间和VR亚临床功能障碍之间的关联.
主要成果:
- 在基线时,26名患者患有RV亚临床功能障碍,其特点是较高的PVC负担和QRS持续时间.
- PVC负荷≥21%和QRS持续时间≥138毫秒独立地与VR亚临床功能障碍相关.
- 在RV自由壁纵向应变 (FWLS) 和全球纵向应变 (GLS) 的显著改善被观察到,特别是在基线RV功能障碍的患者中.
结论:
- 患有RV亚临床功能障碍的患者表现出更高的PVC负担和更长的QRS持续时间.
- 成功的PVC切除可以导致RV功能显著改善,特别是在那些有先前存在的亚临床功能障碍的人中.
- 较低的初始FWLS和GLS预测RV功能在切除后的改善.
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