慢性压力暴露和压力评估对年轻成年人血管内皮功能的相互作用
Alyssa S Carlson1, Laura E Schwager2, Thomas W Hart2
1Psychological and Brain Sciences, University of Iowa, Iowa City, Iowa, United States.
Journal of applied physiology (Bethesda, Md. : 1985)
|January 15, 2025
概括
慢性压力暴露对年轻成年人的血管内皮功能 (VEF) 有负面影响. 然而,高感知压力可以掩盖这种关联,这表明压力敏感性可能会增加脆弱性.
科学领域:
- 心血管生理学心血管生理学
- 心理神经免疫学 心理神经免疫学
- 压力和健康研究 压力和健康研究
背景情况:
- 慢性压力是年轻人日益关注的一个问题.
- 了解压力对血管健康的影响对于预防策略至关重要.
- 血管内皮功能 (VEF) 是心血管风险的早期指标.
研究的目的:
- 调查慢性压力暴露与年轻成年人VEF压力评估之间的关联.
- 确定压力评估是否能缓和慢性压力暴露和VEF之间的关系.
- 探索与慢性压力和VEF相关的高感知压力相关的因素.
主要方法:
- 72名健康的年轻人 (平均年龄25岁) 参与了这项研究.
- 测量了过去一年的慢性压力暴露和评估.
- 使用感知压力量表 (PSS) 评估感知压力.
- 血管内皮功能 (VEF) 使用臂动脉流介导扩张进行了评估.
主要成果:
- 慢性压力暴露与减少的VEF显著相关 (β = -0.24,P = 0.045).
- 感知到的压力减轻了慢性压力暴露对VEF的影响 (P = 0.046).
- 慢性压力和VEF之间的关联在PSS得分大约为22或更高时并不显著.
- 高的PSS得分 (≥22) 与增加的不良童年经历,抑郁症状和减少的弹性有关.
结论:
- 持续的慢性压力暴露是年轻成年人受损VEF的重要预测因素.
- 慢性压力和VEF之间的关系受到感知压力水平的影响.
- 具有高感知压力的年轻人可能特别容易受到与压力相关的血管损伤的影响,可能是由于潜在的压力敏感性.
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