结性脊柱炎生物治疗的全球研究趋势:一个全面的可视化和文献计量研究 (2004-2023)
Weiliang He1, Haicheng Yang2, Xuanzhe Yang1
1Institute of Orthopaedics, Xijing Hospital, Air Force Medical University, Xi'an, China.
Human vaccines & immunotherapeutics
|January 15, 2025
概括
生物疗法为结性脊柱炎 (AS) 患者提供了新的希望. 研究显示,AS和生物治疗研究的全球增加,其中"janus激酶抑制剂"和"secukinumab"成为关键领域.
科学领域:
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
- 图书统计学 图书统计学
背景情况:
- 化脊柱炎 (AS) 是一种影响脊柱的慢性炎症性疾病.
- 生物疗法越来越多地被认为对治疗AS的有效性.
研究的目的:
- 分析全球结性脊柱炎和生物治疗的研究趋势.
- 确定研究热点和AS治疗的未来方向.
主要方法:
- 从2004年到2023年,对2,243篇文章进行了图书统计分析.
- 搜索的数据库:科学网,Scopus,PubMed.搜索的数据库:科学网,Scopus,PubMed.搜索的数据库:科学网,Scopus,PubMed.搜索的数据库:科学网,Scopus,PubMed.搜索的数据库:科学网,Scopus.
- 使用VOSviewer和CiteSpace进行数据可视化.
主要成果:
- 关于AS和生物治疗的出版物每年增加.
- 美国在研究成果方面处于领先地位,其次是意大利,英国,德国和西班牙.
- "Janus激酶抑制剂" (JAKi) 和"secukinumab" (IL-17抑制剂) 是当前的研究热点.
结论:
- 在过去二十年中,AS和生物疗法的全球研究显著增长.
- 美国是主要的贡献者,中国取得了显著的进展.
- 雅克抑制剂和IL-17抑制剂代表了AS有前途的治疗途径.
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