高血压患者的超声波损伤:系统性审查和元分析
Roy Novri Ramadhan1, Derren David Christian Homenta Rampengan2, Felicia Angelica Gunawan2
1Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
PloS one
|January 15, 2025
概括
基于超声波的脏缩 (uRDN) 在高血压患者中显著降低血压. 这种非药理学方法为治疗耐药高血压提供了有前途的治疗方法.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 医疗器械 医疗器械
背景情况:
- 在全球范围内,高血压影响了128亿人,对严重或耐药病例构成挑战.
- 基于超声波的脏缩 (uRDN) 是一种新兴的非药物治疗方法.
- 对抗性高血压的有效管理仍然是一个重大的临床挑战.
研究的目的:
- 调查基于超声波的脏缩 (uRDN) 的安全性和有效性.
- 评估RRDN作为高血压患者的治疗方法,特别是那些有抗性高血压的患者.
主要方法:
- 在多个数据库 (PubMed,ScienceDirect,BMJ期刊,ProQuest,Springer) 进行了系统的文献搜索.
- 经过严格的过和资格评估,八项研究被纳入了定量综合 (元分析).
- 使用RoB 2.0进行了质量评估,并使用RevMan 5.4.4进行了元分析.
主要成果:
- 与对照组相比,urDN显示24小时 (-0.84 mmHg),白天 (-1.27 mmHg) 和家庭 (-1.98 mmHg) 血压测量显著降低.
- 办公室的门诊测量也显示了明显的减少,有利于RRDN (MD-1.51 mmHg).
- 观察到适度的异质性,漏斗图显示了研究中的潜在异常值和真正的异质性.
结论:
- 基于超声波的脏缩 (uRDN) 与高血压患者显著降低血压有关.
- 这些发现支持RRDN作为高血压管理的有效治疗选择,包括耐药病例.
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