为了生活在父母精神分裂史的MESS:对发育检查点的系统审查
Maryam Khan1, Rabia Batool2, Uzma Mushtaq3
1SWPS University, Wroclaw, Poland.
PloS one
|January 15, 2025
概括
父母有精神分裂症病史的儿童表现出发育上的差异. 早期识别运动,情绪,言语和社会认知问题可以指导预防性干预.
科学领域:
- 儿童心理学 儿童心理学
- 发育神经科学的发展神经科学.
- 精神病学遗传学 精神病学遗传学
背景情况:
- 父母患有精神分裂症的病史是后代患上这种疾病的重要风险因素.
- 风险儿童在疾病发作之前的发育轨迹没有得到充分的记录.
- 了解这些早期模式对于及时干预和预防至关重要.
研究的目的:
- 系统地审查和记录父母有精神分裂症病史的儿童的发育模式.
- 确定预防精神病并发症的关键发育检查点.
- 突出早期干预关注的领域.
主要方法:
- 对同行评审文章进行全面的文献综述.
- 在Web of Science,PubMed和PsychInfo数据库中进行的搜索.
- 对有和没有父母精神分裂症病史的儿童发育模式的比较分析.
主要成果:
- 父母有精神分裂症病史的儿童表现出不同的发育模式.
- 确定的主要关注领域包括运动,情绪,行为,言语,听力和社会认知领域.
- MESS类型 (运动,情绪/行为,言语/听力,社会认知) 提供了评估的框架.
结论:
- 早期和系统地监测发育里程碑对于有风险的儿童至关重要.
- 专注于确定发育领域的干预可以减轻与父母精神分裂症病史相关的风险.
- 本综述为预防精神分裂症父母后代的心理并发症提供了一份指南.
相关概念视频
Psychological and Sociocultural Causes of Schizophrenia
53
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
53
Biological Causes of Schizophrenia
38
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
38
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
417
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
417
Schizophrenia
64
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
64
Autism Spectrum Disorder
57
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
57
Meiosis I
38.0K
Meiosis is the division of a diploid cell into haploid cells forming sperm and eggs in animals through differentiation. Meiosis I is the first stage of meiosis, where the genetic recombination of homologous chromosomes and the reduction of the ploidy level by half occurs.
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
38.0K


