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Updated: Jun 2, 2025

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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Published on: December 7, 2014

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临床上先进的BDK抑制剂

Kukkamudi Sreenivas1, Chintada Nageswara Rao1

  • 1Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia SC-29208, United States.

Journal of medicinal chemistry
|January 15, 2025
PubMed
概括

心脏病与分支链氨基酸 (BCAA) 不平衡有关. BDK的活性会影响BCAA的代谢. 一种潜在的BDK抑制剂,PF-07328948,正在为心血管疾病 (CVD) 的代谢问题进行临床试验.

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