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Updated: Jun 2, 2025

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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在结直肠癌发生的进展过程中,未折叠的蛋白质反应

Cesar Augusto Sobrinho1, Alexandre Moreira de Almeida1, Maytana Roberta Taschin Grigolo1

  • 1Universidade Federal de Mato Grosso do Sul - Postgraduate Program in Health and Development in the Midwest Region - Campo Grande (MS) - Brazil.

Acta cirurgica brasileira
|January 15, 2025
PubMed
概括

在结直肠癌的发展过程中,包括IRE1-α,PERK,ATF6和CHOP在内的内质网膜 (ER) 压力标志物显著上调,这表明细胞反应强烈. 这种分子进化突出了ER压力作为癌症进展的关键因素.

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